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Wednesday, March 9th, 2016

  • Arrival of external organizers and speakers
  • Registration, free workshop from sponsors
  • Opportunity to attend the lecture of Randy Schekman
  • Opening session
  • Welcome reception

Thursday, March 10th, 2016

  • Symposium from 9:00 until 18:30 interrupted by coffee breaks and lunch
  • Dinner for organizers and invited speakers only (starting from 19:30)

Friday, March 11th, 2016

  • Departure of external organizers and speakers


Final program of the symposium

Wednesday, March 9th, 2016

13:30           Start of registration for symposium

14:00           Free Workshop (BMG LABTECH GmbH and Luxcel Biosciences Ltd.)

                     Title: Cellular Metabolism Made Easy: Learn how to easily measure oxygen consumption rate and glycolytic flux

                     Venue: FRIAS, Albertstr. 19, Alter Anatomiehörsaal

                     Open to public / no registration needed

16:15           Opportunity to attend the 21st Hermann Staudinger Lecture with Nobel Laureate Randy Schekman (University of California, Berkeley)

                     Title: Unconventional Secretion of Proteins and RNA from Cultured Human Cells

                     Venue: FRIAS, Albertstr. 19, Hörsaal Pathologie/Anatomie

                     Open to public / no registration needed

18:00           Welcome to the 2nd International Symposium: One mitochondrion, many diseases (Opening remarks, Verónica Dumit)

                     Venue: FRIAS, Albertstr. 19, Großer Seminarraum

Session I (18:15-19:15; Chair: Verónica Dumit)

18:15           Opening lecture: Jörn Dengjel, Deregulated Mitochondrial Protein Homeostasis and Its Role in Disease

18:45           Jan Riemer, Thiol Oxidation in Respiratory Chain Assembly and Calcium Signaling

19:15           Welcome reception


Thursday, March 10th, 2016

09:00           Opening remarks (Ralf Braun)

Session II (09:15-10:55; Chair: Ralf Braun)

09:15           Martin van der Laan: Biogenesis and Functional Architecture of Mitochondrial Membranes

09:45           Ralf Zerbes: The Mitochondrial Contact Site and Cristae Organising System - Form Meets Function

10:05           Iain Johnston: MtDNA Evolution within Cells and the Inheritance and Onset of Mitochondrial Diseases

10:35           Denis Gris: Role of Mitochondria in Inflammation during Neurodegenerative Diseases

10:55           Coffee break

Session III (11:15-12:55; Chair: Ralf Zerbes)

11:15           Konstanze Winklhofer: Ubiquitin Signaling and Mitochondrial Integrity: Implications for Parkinson's Disease

11:45           Florian Steinberg: Role of Endocytic Rab GTPases in Mitophagy

12:05           Ulrich Brandt: Structure, Function and Regulation of Mitochondrial Complex I

12:35           Verónica Dumit: Emodin Affects Mitochondrial Homeostasis Leading to a Differential Response of Healthy and Cancer Cells

12:55           Lunch

Session IV (14:25-15:45; Chair: Florian Steinberg)

14:25           Hans Zischka: Mitochondrial Toxicology: Rescuing Mitochondria in Wilson Disease Avoids Acute Liver Failure

14:55           Janina Bergmann: Are Mitochondria from "Iron-Sulfur Disease" Patients Removed via PINK1-Parkin-Dependent Mitophagy?

15:15           Xavier Roucou: MID51/Mief1 Codes for Two Different Proteins, Both Involved in Mitochondrial Fission

15:45           Poster session, meet the sponsors & coffee break

Session V (16:30-18:10; Chair: Denis Gris)

16:30           Nora Vögtle: Mitochondrial Presequence Proteases in Health and Disease

17:00           Ralf Braun: Mitochondrial Proteostasis Dictates the Cytotoxicity of Alzheimer’s Disease-Associated Ubiquitin

17:20           Julia Ring: Cytosolic Abeta Targets Mitochondria Inducing Cell Death in a Yeast Model of AD

17:50           Alice Rossi: Effects of Presenilin 2 Mutations Associated with Familial Alzheimer's Disease on Mitochondrial Functionality

18:10           Concluding remarks (Denis Gris)

19:30          Dinner (for organizers and invited speakers only)